TY - JOUR ID - 39520 TI - First Reported Case of Reactive Airway Dysfunction Syndrome in a Laborer Due to Porcelain Tile Dust JO - Iranian Journal of Medical Sciences JA - IJMS LA - en SN - 0253-0716 AU - Arif, Tasleem AU - Ahmad Malik, Javid AU - Shoib, Sheikh AD - Resident of Chest Medicine, SKIMS Medical College/Hospital Srinagar, Jammu and Kashmir, India AD - Department of Chest Medicine, SKIMS Medical College/Hospital Srinagar, Jammu and Kashmir, India Y1 - 2013 PY - 2013 VL - 38 IS - 2 SP - 132 EP - 134 KW - Porcelain KW - Dust KW - RADS DO - N2 - Reactive airway dysfunction syndrome (RADS) is a type of non-immunologically mediated asthma-like disease. It usually occurs after a massive exposure to an irritating substance in the atmosphere in the form of smoke, fumes, gases, and vapor. Unlike bronchial asthma, there is no latency to the symptoms seen in RADS. A number of agents are known to cause RADS, but tile dust, as an etiological agent, has not been previously reported. We report a 45-year-old male laborer, who presented with an acute onset of cough, chest tightness, breathlessness, and audible wheeze after his first time exposure to porcelain tile dust within 5 hours of exposure. Lab tests, including, chest X-ray, electrocardiogram, air blood gas analysis, and serum IgE, were unremarkable. Spirometry showed a mild obstruction [forced expiratory volume in 1 second (FEV1)=72% of predicted], while the bronchodilator reversibility test was significant(14% increase in FEV1 above the baseline).Bronchial biopsy revealed a chronic inflammatory reaction with lymphocytic and plasma cell infiltration and more importantly a striking absence of eosinophils. To the best of our knowledge, this is the first reported case of RADS as a result of exposure to tile dust (porcelain ceramics). UR - https://ijms.sums.ac.ir/article_39520.html L1 - https://ijms.sums.ac.ir/article_39520_6a8ab35458b8292a2521027efacb36db.pdf ER -