TY - JOUR ID - 44096 TI - Epidemiology of Inflammatory Bowel Diseases in Iran and Asia; A Mini Review JO - Iranian Journal of Medical Sciences JA - IJMS LA - en SN - 0253-0716 AU - Mehrabani, Davood AU - Safarpour, Ali Reza AU - Hosseini, Seyed Vahid AD - Stem Cell and Transgenic Technology Research Center, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran AD - Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran AD - Laparoscopy Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Y1 - 2013 PY - 2013 VL - 38 IS - June Supplement 2013 SP - 140 EP - 149 KW - Inflammatory bowel disease KW - Epidemiology KW - prevalence KW - Iran DO - 10.30476/ijms.2013.44096 N2 - The prevalence of inflammatory bowel diseases (IBDs) is set to stabilize in Western Europe and North America, as opposed to its increasing trend in developing countries in Asia. The epidemiology of IBDs in areas where the incidence and prevalence are relatively low provides an opportunity for researchers to determine the unknown aspects of them. In this review article, the PubMed and MEDLINE databases were searched from 1970 to 2012 and the epidemiological aspects assessed in Iranian articles were compared with identical subjects in other Asian countries. During this period, there were 21 documented articles on IBD epidemiology in Iran and 52 in Asia. According to the present review, CTLA-gene polymorphism and male/female ratio in ulcerative colitis (UC), incidence of extra-intestinal manifestations, extent of intestinal involvement, and family history in both UC and Crohn's disease (CD) seemed to be different between Asia and Iran. In contrast, the incidence of primary sclerosing cholangitis in IBD patients and association between NO2/CARD15 mutation and CD as C3435-T allele and UC were nearly the same. The rate of IBD has increased significantly in Iran, as has that of other Asian countries during the last decade. A thorough, well-designed, population-based, multi-regional epidemiologic study seems mandatory due to the substantial demographic and characteristic variability in IBD patients in our region. UR - https://ijms.sums.ac.ir/article_44096.html L1 - https://ijms.sums.ac.ir/article_44096_e6ab44573f219ab1ec6610a092c8d7ee.pdf ER -