Iranian Journal of Medical Sciences

Document Type: Case Report(s)



Acute myelogenous leukemia (AML) is a hematological malignancy, which accounts for about 15-25% of childhood's leukemia. Genetic factor is one of the most important predisposing elements in childhood acute leukemia, especially AML. In this case report, a rare presentation of familial AML is presented in three monozygotic triplets. Two were 10 months old, and the other one was 16 months old at presentation. Chemotherapeutic regimen was administered for all three sisters with good response and success in maintaining remission.Iran J Med Sci 2006; 31(4): 228-231. Keywords ● Familial AML ● monozygotic triplets ● chemotherapy ● remission