Antireflux Valve in Post Cholecystojeju-nostomy Cholangitis: An Animal Study

H.R. Foroutan, U. Dasmeh, B. Geramizadeh, H.R. Kamalipour, N. Tanideh


Background: One of the most important post-operation problems encountered with Hepaticojejunostomy (Kasai operation) in patients with biliary atresia is cholangitis. The aim of this study was to evaluate the efficiency of anti-reflux valve in decreasing the incidence of cholangitis after hepaticojejunostomy.


Methods: Ten dogs were randomly divided into two groups of equal size. In group A Roux-en-Y cholecystojejunostomy was performer and in group B antireflux valve was also added. Three months later, liver biopsy was taken to evaluate histopatholic changes.


Results: The incidence of cholangitis was significantly reduced in dogs in which anti-reflux valve procedure was performed.


Conclusions: Anti-reflux valve procedure effectively decreased post-Roux-en-Y cholecystojejunostomy cholangitis in dogs. Therefore it is plausible and might be beneficial for patients being treated for biliary atresia.

Iran J Med Sci 2006; 31(2): 91-93.


Keywords Cholangitis Kasai operation antireflux valve Roux-en-Y cholecystojejunostomy

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pISSN: 0253-0716         eISSN: 1735-3688