%0 Journal Article %T Effects of Tranexamic Acid on Bleeding and Hemoglobin Levels in Patients Undergoing Percutaneous Nephrolithotomy: Letter to Editor %J Iranian Journal of Medical Sciences %I Shiraz University of Medical Sciences %Z 0253-0716 %A Shahriari, Mahdi %D 2020 %\ 03/01/2020 %V 45 %N 2 %P 148-149 %! Effects of Tranexamic Acid on Bleeding and Hemoglobin Levels in Patients Undergoing Percutaneous Nephrolithotomy: Letter to Editor %K Tranexamic acid %R 10.30476/ijms.2020.84261.1382 %X With great interest, I read a recently published article (IJMS issue: Volume 44, number 6, November 2019) by Mohammadi and colleagues titled “Effects of tranexamic acid on bleeding and hemoglobin levels in patients with staghorn calculi undergoing percutaneous nephrolithotomy”. In their randomized controlled trial, they evaluated the effect of Tranexamic acid (TXA), as an anti-fibrinolytic agent, in preventing excessive bleeding after percutaneous nephrolithotomy (PCNL). They concluded that “TXA reduced the risk of bleeding during and after PCNL and attenuated the drop in the hemoglobin level in the postoperative period”. Furthermore, in the methods section, they stated: “The exclusion criteria comprised of intravascular coagulation, skeletal disorders, acquired color vision, subarachnoid hemorrhage, drug sensitization, and non-consumption of aspirin, warfarin, or vitamin E”. %U https://ijms.sums.ac.ir/article_46356_da9c8f0cb7df56f9b332bdba6580a441.pdf