Iranian Journal of Medical Sciences

Document Type : Case Report(s)

Authors

Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai, Tamil Nadu, India

Abstract

Calcifying epithelial odontogenic tumor is a rare odontogenic neoplasm. Its occurrence in the maxillary sinus is very rare. Maxillary tumors tend to be locally aggressive and may rapidly involve the surrounding vital structures.  We report a case of calcifying epithelial odontogenic tumor involving maxillary sinus in a 48 years old female patient with the oral mucosal involvement. The purpose of this article is to report an additional case of calcifying epithelial odontogenic tumor and discuss the radiologic appearance, histologic features, and to highlight its clinical behavior.

Keywords

  1. Thoma KH, Goldman HM. Odontogenic tumors: classification based on observations of the epithelial, mesenchymal, and mixed varieties. Am J Pathol. 1946;22:433-71. PubMed PMID: 21028226.
  2. Reichart PA, Philpsen HP. Odontogenic tumors and allied lesions. London: Quintessence; 2004. p. 93-104.
  3. Philipsen HP, Reichart PA. Calcifying epithelial odontogenic tumour: biological profile based on 181 cases from the literature. Oral Oncol. 2000;36:17-26. doi: 10.1016/S1368-8375(99)00061-5. PubMed PMID: 10889914.
  4. Goode RK. Calcifying epithelial odontogenic tumor. Oral Maxillofac Surg Clin North Am. 2004;16:323-31. doi: 10.1016/j.coms.2004.03.002. PubMed PMID: 18088734.
  5. Mohtasham N, Habibi A, Jafarzadeh H, Amirchaghmaghi M. Extension of Pindborg tumor to the maxillary sinus: a case report. J Oral Pathol Med. 2008;37:59-61. doi: 10.1111/j.1600-0714.2007.00567.x. PubMed PMID: 18154580.
  6. Ng KH, Siar CH. A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians. J Laryngol Otol. 1996;110:757-62. doi: 10.1017/S0022215100134887. PubMed PMID: 8869610.
  7. Vinayakrishna K, Soumithran CS, Sobhana CR, Biradar V. Peripheral and central aggressive form of Pindborg tumor of mandible - A rare case report. J Oral Biol Craniofac Res. 2013;3:154-8. doi: 10.1016/j.jobcr.2013.07.001. PubMed PMID: 25737906; PubMed Central PMCID: PMC4306990.
  8. Ching AS, Pak MW, Kew J, Metreweli C. CT and MR imaging appearances of an extraosseous calcifying epithelial odontogenic tumor (Pindborg tumor). AJNR Am J Neuroradiol. 2000;21:343-5. PubMed PMID: 10696021.
  9. Uchiyama Y, Murakami S, Kishino M, Furukawa S. CT and MR imaging features of a case of calcifying epithelial odontogenic tumor. JBR-BTR. 2012;95:315‑9. doi: 10.5334/jbr-btr.676. PubMed PMID: 23198374.
  10. Maria A, Sharma Y, Malik M. Calcifying epithelial odontogenic tumour: a case report. J Maxillofac Oral Surg. 2010;9:302-6. doi: 10.1007/s12663-010-0068-x. PubMed PMID: 22190811; PubMed Central PMCID: PMC3177451.
  11. Barnes El, Eveson JW, Reichart P, Sidransky D. Pathology and Genetics of Head and Neck Tumours WHO Classification of Tumours. Lyon: IARC; 2005. p. 302-3.
  12. Chen CY, Wu CW, Wang WC, Lin LM, Chen YK. Clear-cell variant of calcifying epithelial odontogenic tumor (Pindborg tumor) in the mandible. Int J Oral Sci. 2013;5:115-9. doi: 10.1038/ijos.2013.29. PubMed PMID: 23703711; PubMed Central PMCID: PMC3707072.
  13. Friedrich RE, Zustin J. Calcifying epithelial odontogenic tumour of the maxilla: a case report with respect to immunohistochemical findings. In Vivo. 2011;25:259-64. PubMed PMID: 21471544.
  14. Abrahao AC, Camisasca DR, Bonelli BR, Cabral MG, Lourenco SQ, Torres SR, et al. Recurrent bilateral gingival peripheral calcifying epithelial odontogenic tumor (Pindborg tumor): a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:e66-71. doi: 10.1016/j.tripleo.2009.04.037. PubMed PMID: 19716494.