Herein, we report on a 24-year-old woman with a large well-marginated gastric mucosa-associated lymphoid tissue (MALT) lymphoma. She presented with dysphagia and epigastric pain. In esophagogastroduodenoscopy there was a huge bulging submucosal mass with normal appearing mucosa in the cardia in addition to a grade B gastro-esophageal reflux disease. She was treated with a proton pump inhibitor and an intramural gastric mass was confirmed by a computed tomography scan. She underwent surgical operation and was well in her last follow-up visit after 16 months.