@article { author = {Asmarian, Naeimehossadat and Zand, Farid and Delavari, Parvin and Khaloo, Vahid and Esmaeilinezhad, Zahra and Sabetian, Golnar and Moeini, Yaldasadat and Savaie, Mohsen and Javaherforooshzadeh, Fatemeh and Soltani, Farhad and Yousefi, Farid and Heidari Sardabi, Ebrahim and Haddadzadeh Shoushtari, Maryam and Dehnadi Moghadam, Anoush and Dehnadi Moghadam, Fatemeh and Gholami, Somayeh}, title = {Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study}, journal = {Iranian Journal of Medical Sciences}, volume = {47}, number = {5}, pages = {450-460}, year = {2022}, publisher = {Shiraz University of Medical Sciences}, issn = {0253-0716}, eissn = {1735-3688}, doi = {10.30476/ijms.2021.89916.2068}, abstract = {Background: The coronavirus disease 2019 (COVID-19) has become the leading source of pneumonia outbreaks in the world. The present study aimed to compare the condition of intensive care unit (ICU) and non-ICU COVID-19 patients in terms of epidemiological and clinical features, laboratory findings, and outcomes in three cities across Iran.Methods: In a cross-sectional study, 195 COVID-19 patients admitted to five hospitals across Iran during March-April 2020 were recruited. Collected information included demographic data, laboratory findings, symptoms, medical history, and outcomes. Data were analyzed using SPSS software with t test or Mann-Whitney U test (continuous data) and Chi square test or Fisher’s exact test (categorical variables). P<0.05 was considered statistically significant.Results: Of the 195 patients, 57.4% were men, and 67.7% had at least one comorbidity. The prevalence of stroke, chronic obstructive pulmonary disease, and autoimmune diseases was higher in ICU than in non-ICU patients (P=0.042, P=0.020, and P=0.002, respectively). Compared with non-ICU, ICU patients had significantly higher white blood cell (WBC) count (P=0.008), cardiac troponin concentrations (P=0.040), lactate dehydrogenase levels (P=0.027), erythrocyte sedimentation rates (P=0.008), and blood urea nitrogen (BUN) (P=0.029), but lower hematocrit levels (P=0.001). The mortality rate in ICU and non-ICU patients was 48.1% and 6.1%, respectively. The risk factors for mortality included age>40 years, body mass index<18 Kg/m2, hypertension, coronary artery disease, fever, cough, dyspnea, ST-segment changes, pericardial effusion, and a surge in WBC and C-reactive protein, aspartate aminotransferase, and BUN. Conclusion: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors.}, keywords = {COVID-19,SARS-CoV-2,Dyspnea,Pneumonia,Intensive care unit}, url = {https://ijms.sums.ac.ir/article_48348.html}, eprint = {https://ijms.sums.ac.ir/article_48348_9e2130ffba68a86e35ce0964a81e114a.pdf} }