%0 Journal Article %T Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study %J Iranian Journal of Medical Sciences %I Shiraz University of Medical Sciences %Z 0253-0716 %A Asmarian, Naeimehossadat %A Zand, Farid %A Delavari, Parvin %A Khaloo, Vahid %A Esmaeilinezhad, Zahra %A Sabetian, Golnar %A Moeini, Yaldasadat %A Savaie, Mohsen %A Javaherforooshzadeh, Fatemeh %A Soltani, Farhad %A Yousefi, Farid %A Heidari Sardabi, Ebrahim %A Haddadzadeh Shoushtari, Maryam %A Dehnadi Moghadam, Anoush %A Dehnadi Moghadam, Fatemeh %A Gholami, Somayeh %D 2022 %\ 09/01/2022 %V 47 %N 5 %P 450-460 %! Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study %K COVID-19 %K SARS-CoV-2 %K Dyspnea %K Pneumonia %K Intensive care unit %R 10.30476/ijms.2021.89916.2068 %X Background: The coronavirus disease 2019 (COVID-19) has become the leading source of pneumonia outbreaks in the world. The present study aimed to compare the condition of intensive care unit (ICU) and non-ICU COVID-19 patients in terms of epidemiological and clinical features, laboratory findings, and outcomes in three cities across Iran.Methods: In a cross-sectional study, 195 COVID-19 patients admitted to five hospitals across Iran during March-April 2020 were recruited. Collected information included demographic data, laboratory findings, symptoms, medical history, and outcomes. Data were analyzed using SPSS software with t test or Mann-Whitney U test (continuous data) and Chi square test or Fisher’s exact test (categorical variables). P<0.05 was considered statistically significant.Results: Of the 195 patients, 57.4% were men, and 67.7% had at least one comorbidity. The prevalence of stroke, chronic obstructive pulmonary disease, and autoimmune diseases was higher in ICU than in non-ICU patients (P=0.042, P=0.020, and P=0.002, respectively). Compared with non-ICU, ICU patients had significantly higher white blood cell (WBC) count (P=0.008), cardiac troponin concentrations (P=0.040), lactate dehydrogenase levels (P=0.027), erythrocyte sedimentation rates (P=0.008), and blood urea nitrogen (BUN) (P=0.029), but lower hematocrit levels (P=0.001). The mortality rate in ICU and non-ICU patients was 48.1% and 6.1%, respectively. The risk factors for mortality included age>40 years, body mass index<18 Kg/m2, hypertension, coronary artery disease, fever, cough, dyspnea, ST-segment changes, pericardial effusion, and a surge in WBC and C-reactive protein, aspartate aminotransferase, and BUN. Conclusion: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors. %U https://ijms.sums.ac.ir/article_48348_9e2130ffba68a86e35ce0964a81e114a.pdf