TY - JOUR ID - 48282 TI - Association of Non-Melanoma Skin Cancer with Temperament from the Perspective of Traditional Persian Medicine: A Case-Control Study JO - Iranian Journal of Medical Sciences JA - IJMS LA - en SN - 0253-0716 AU - Parvizi, Mohammad Mahdi AU - Ghahartars, Mehdi AU - Jowkar, Zeynab AU - Saki, Nasrin AU - Kamgar, Mahtab AU - Hosseinpour, Parisa AU - Zare, Hamid AU - Sari Aslani, Fatemeh AD - Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AD - Molecular Dermatology Research Center, Department of Dermatology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran AD - Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran AD - Department of Dermatology, School of Medicine, Islamic Azad University, Kazeroon Branch, Iran AD - Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Y1 - 2022 PY - 2022 VL - 47 IS - 5 SP - 477 EP - 483 KW - Traditional KW - Skin neoplasms KW - Temperament KW - Persian medicine DO - 10.30476/ijms.2021.91265.2239 N2 - Background: Non-melanoma skin cancer (NMSC) is the most common type of cancer in the world. In traditional Persian medicine (TPM), various types of temperament (Mizaj) are considered to diagnose, treat, and prevent a variety of illnesses. The present study aimed to evaluate the temperament of patients with NMSC in comparison with a control group.Methods: A case-control study was conducted in 2018 at the Dermatology Clinic of Shahid Faghihi Hospital affiliated with Shiraz University of Medical Sciences (Shiraz, Iran). A total of 110 patients, aged ≥20 years with confirmed NMSC (case group), and 181 individuals without NMSC (control group) were enrolled in the study. The temperament of the participants in both groups was evaluated using Mojahedi’s Mizaj questionnaire. The data were analyzed using SPSS software, and P<0.05 was considered statistically significant.Results: The results showed that the odds ratio of developing NMSC was 2.62 (95%CI: 1.42-4.83, P=0.002) times higher in individuals with dry temperament than other types of temperament. Moreover, the odds ratio of patients with a history of chronic skin ulcers and other types of cancer was 35.7 (95%CI: 11.9-107.15, P<0.001) and 5.22 (95%CI: 1.43-19.06, P=0.012) times higher, respectively, than the control group. Conclusion: Temperament is associated with NMSC, particularly the dry temperament type, and should be considered a risk factor. UR - https://ijms.sums.ac.ir/article_48282.html L1 - https://ijms.sums.ac.ir/article_48282_7c1392b1f8f74677ebd153a16a450969.pdf ER -