Document Type : Case Report(s)

Authors

• Maryam Mobini ¹
• Hamed Cheraghmakani ²
• Zhila Torabizadeh ³
• Omid Emadian ³
• Fatemeh Nezhadi Kelarijani ⁴

¹ Diabetes Research Center, Department of Internal Medicine, Mazandaran University of Medical Sciences, Sari, Iran

² Department of Neurology, Bu Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran

³ Department of Pathology, Mazandaran University of Medical Sciences, Sari, Iran

⁴ Resident in Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Abstract

Eosinophilic granulomatosis with polyangiitis formerly named “Churg-Strauss syndrome (CSS)” is a systemic disease with bronchial asthma, hypereosinophilia, and systemic vasculitis. We report a case of CSS with cholecystitis and mononeuritis multiplex. A 50-year-old woman with a history of sinusitis and bronchial asthma of 8 years’ duration was referred with a complaint of left-hand deformity and difficulty in walking. The laboratory findings included remarkable eosinophilia, an elevated erythrocyte sedimentation rate, and a marked eosinophilic infiltration in the gallbladder biopsy. Based on the clinical features and histopathological findings, she was diagnosed with CSS and subsequently treated with prednisolone and cyclophosphamide.

Keywords

• Churg-Strauss syndrome
• Cholecystitis
• Mononeuropathies