Iranian Journal of Medical Sciences

Document Type: Original Article(s)


1 Department of Community Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

2 Department of Community Medicine, Birjand University of Medical Sciences, Birjand, Iran

3 Department of Obstetrics and Gynecology, Akbar Abadi Hospital, Tehran University of Medical Sciences, Tehran, Iran


Background: The Endometriosis Health Profile-30 (EHP-30) is a disease-specific questionnaire to measure the health-related quality of life in patients with endometriosis. The aim of this study was to evaluate the validity and reliability of the Persian version of Endometriosis Health Pro-file (EHP-30) in women with endometriosis referring to three Gynecology Clinics in Tehran, Iran.
Methods: One hundred women (20 to 50 years old) with surgically confirmed endometriosis recruited from three outpatient Gynecology Clinics affiliated to the Iran University of Medical Sciences. All 100 patients were asked to complete EHP-30 questionnaire while referring to the Clinics. The findings were analyzed using descriptive statistics, internal reliability consistency, construct validity (using short form-36, which had already been validated in Iran), factor analysis (with principle component analysis method), and item total correlation to assess the validity and reliability of the questionnaire.
Results: The internal consistency reliability of the questionnaire was high (Cronbach’s α ranged between 0.80 and 0.93 for core, and 0.78 and 0.90 for modular parts). All items were loaded on their own factors except item 17 (feeling aggressive or violent) and item 18 (feeling unwell), which were loaded on pain and social support domains, respectively. Construct validity of EHP-30, established by using SF-36, indicates good correlations in several similar scales of these two questionnaires.
Conclusion: The findings of the study demonstrate that Persian version of EHP-30 is a valid and reliable measure to assess the quality of life in women with endometriosis.