Iranian Journal of Medical Sciences

Document Type : Original Article(s)


National Institute of Population Research, Tehran, Iran


Background: The COVID-19 pandemic has caused a significant number of deaths in many countries around the world. This study provides an estimate of the effect of the COVID-19 epidemic on life expectancy and years of life lost (YLL) in Iran.
Methods: This study is a secondary data analysis carried out in 2020. Mortality data from COVID-19 were obtained from the Ministry of Health and Medical Education. Since the calculation of mortality rates requires the number of people at risk of death, this data was obtained from the Statistics Center of Iran and was used after a detailed evaluation. The effect of COVID-19 on mortality is evaluated using the techniques of a multi-decrement life table and the corresponding single-reduction life table. The YLL is calculated using the standard method provided by the World Health Organization.
Results: Analysis of mortality data showed that deaths due to COVID-19 could reduce life expectancy at birth by 1.4 years in 2020. Therefore, life expectancy at birth declined from 75.1 years to 73.7 years. Furthermore, the deaths due to COVID-19 from the outbreak to early February 2021 have caused about 800,000 years of YLL, which is almost as much as the YLL caused by cancers and tumors.
Conclusion: A decrease in life expectancy at birth by more than one year in countries with a life expectancy of over 70 years, such as Iran, can delay the increase in life expectancy for several years.


  1. Ullah MA, Moin AT, Araf Y, Bhuiyan AR, Griffiths MD, Gozal D. Potential Effects of the COVID-19 Pandemic on Future Birth Rate. Front Public Health. 2020;8:578438. doi: 10.3389/fpubh.2020.578438. PubMed PMID: 33363080; PubMed Central PMCID: PMCPMC7758229.
  2. Institute of Medicine (US) Forum on Microbial Threats. Microbial Evolution and Co-Adaptation: A Tribute to the Life and Scientific Legacies of Joshua Lederberg: Workshop Summary. Washington: National Academies Press; 2009. PubMed PMID: 20945572.
  3. Bloom DE, Kuhn M, Prettner K. Modern infectious diseases: Macroeconomic impacts and policy responses. National Bureau of Economic Research, 2020. doi: 10.3386/w27757.
  4. Caldwell JC. Population health in transition. Bull World Health Organ. 2001;79:159-60. PubMed PMID: 11242823; PubMed Central PMCID: PMCPMC2566355.
  5. Omran AR. The epidemiologic transition. A theory of the Epidemiology of population change. 1971. Bull World Health Organ. 2001;79:161-70. PubMed PMID: 11246833; PubMed Central PMCID: PMCPMC2566347.
  6. Olshansky SJ, Carnes B, Rogers RG, Smith L. Infectious diseases -- new and ancient threats to world health. Popul Bull. 1997;52:1-52. PubMed PMID: 12292663.
  7. Olshansky SJ, Ault AB. The fourth stage of the epidemiologic transition: the age of delayed degenerative diseases. Milbank Q. 1986;64:355-91. PubMed PMID: 3762504.
  8. Trias-Llimos S, Bilal U. Impact of the COVID-19 pandemic on life expectancy in Madrid (Spain). J Public Health (Oxf). 2020;42:635-6. doi: 10.1093/pubmed/fdaa087. PubMed PMID: 32542350; PubMed Central PMCID: PMCPMC7337791.
  9. Andrasfay T, Goldman N. Reductions in 2020 US life expectancy due to COVID-19 and the disproportionate impact on the Black and Latino populations. Proc Natl Acad Sci U S A. 2021;118. doi: 10.1073/pnas.2014746118. PubMed PMID: 33446511; PubMed Central PMCID: PMCPMC7865122.
  10. Sasanipour M, Mohebi Meymandi M. Assessing the Possibility of Improving Iran’s Life Expectancy by Eliminating Major Causes of Death During 2006-2015. Population Studies. 2019;5:7-29.
  11. Fathi E, Sharifi M, Ebrahimpour M, Zanjani H. Major causes of mortality in Iran in 2016 Using multiple decrease life tables. Journal of Population Association of Iran. 2019;13:155-85. doi: 20.1001.1.1735000.1397.
  12. Mohammadpour R-A, Khanali F, Yazdani J, Mahmoodi M, Khosravi A. Estimating potential gain in life expectancy by eliminating causes of‎ death in Iran, 2010‎. Journal of Mazandaran University of Medical Sciences. 2014;24:89-95.
  13. UN Statistics Division. Statistical Yearbook. New York: United Nations; 2020.
  14. Lee R. The Lee-Carter method for forecasting mortality, with various extensions and applications. North American actuarial journal. 2000;4:80-91. doi: 10.1080/10920277.2000.10595882.
  15. Iran SCo. Population Data Sheet for the Islamic Republic of Iran 2016. Tehran; 2017. Persian.
  16. MOHME. Age distribution of definite cases and deaths toll COVID-19 to September 19. Tehran: MOHME; 2020. Persian.
  17. Schoen R. Constructing increment-decrement life tables. Demography. 1975;12:313-24. PubMed PMID: 1157991.
  18. Keyfitz N, Caswell H. Applied mathematical demography. New York: Springer; 2005.
  19. Preston SH, Heuveline P, Guillot M. [BOOK REVIEW] Demography, measuring and modeling population processes. Population and Development Review. 2001;27:365-7.
  20. Fewtrell L, Kaufman R, Prüss-Üstün A. Lead: assessing the environmental burden of diseases at national and local levels: Geneva: World Health Organization; 2003.
  21. Aburto JM, Schöley J, Zhang L, Kashnitsky I, Rahal C, Missov TI, et al. Recent Gains in Life Expectancy Reversed by the COVID-19 Pandemic. medRxiv. 2021. doi: 10.1101/2021.03.02.21252772.
  22. Castro MC, Gurzenda S, Turra CM, Kim S, Andrasfay T, Goldman N. Reduction in the 2020 Life Expectancy in Brazil after COVID-19. medRxiv. 2021.
  23. Marois G, Muttarak R, Scherbov S. Assessing the potential impact of COVID-19 on life expectancy. PLoS One. 2020;15:e0238678. doi: 10.1371/journal.pone.0238678. PubMed PMID: 32941467; PubMed Central PMCID: PMCPMC7498023.
  24. Noymer A, Garenne M. The 1918 influenza epidemic’s effects on sex differentials in mortality in the United States. Popul Dev Rev. 2000;26:565-81. doi: 10.1111/j.1728-4457.2000.00565.x. PubMed PMID: 19530360; PubMed Central PMCID: PMCPMC2740912.
  25. Helleringer S, Noymer A. Assessing the direct effects of the ebola outbreak on life expectancy in liberia, sierra leone and Guinea. PLoS Curr. 2015;7. doi: 10.1371/currents.outbreaks.01a99f8342b42a58d806d7d1749574ea. PubMed PMID: 25737805; PubMed Central PMCID: PMCPMC4339316.
  26. Dowd JB, Andriano L, Brazel DM, Rotondi V, Block P, Ding X, et al. Demographic science aids in understanding the spread and fatality rates of COVID-19. Proc Natl Acad Sci U S A. 2020;117:9696-8. doi: 10.1073/pnas.2004911117. PubMed PMID: 32300018; PubMed Central PMCID: PMCPMC7211934.
  27. Kontis V, Bennett JE, Rashid T, Parks RM, Pearson-Stuttard J, Guillot M, et al. Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on all-cause mortality in 21 industrialized countries. Nat Med. 2020;26:1919-28. doi: 10.1038/s41591-020-1112-0. PubMed PMID: 33057181.
  28. Onder G, Rezza G, Brusaferro S. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy. JAMA. 2020;323:1775-6. doi: 10.1001/jama.2020.4683. PubMed PMID: 32203977.
  29. Quast T, Andel R, Gregory S, Storch EA. Years of life lost associated with COVID-19 deaths in the USA during the first year of the pandemic. J Public Health (Oxf). 2021. doi: 10.1093/pubmed/fdab123. PubMed PMID: 33839789; PubMed Central PMCID: PMCPMC8083296.
  30. Vieira A, Ricoca VP, Aguiar P, Sousa P, Nunes C, Abrantes A. Years of life lost by COVID-19 in Portugal and comparison with other European countries in 2020. BMC Public Health. 2021;21:1054. doi: 10.1186/s12889-021-11128-6. PubMed PMID: 34078348; PubMed Central PMCID: PMCPMC8171993.
  31. Woolf SH, Chapman DA, Sabo RT, Zimmerman EB. Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021. JAMA. 2021;325:1786-9. doi: 10.1001/jama.2021.5199. PubMed PMID: 33797550; PubMed Central PMCID: PMCPMC8019132.
  32. Oguzoglu U. COVID-19 lockdowns and decline in traffic related deaths and injuries. 2020. doi: 10.2139/ssrn.3608527.