Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences

Prevalence of Lymph Node Metastasis in Radical Prostatectomy; A Retrospective and Multicenter Study in Iran

Document Type : Brief Report(s)

Authors

Mohsen Ayati
Mohammad Reza Nowroozi
Hassan Jamshidian
Elnaz Ayati
Farhad Zarghan

Uro-Oncology Research Center (UoRC), Tehran University of Medical Sciences, Tehran, Iran

Abstract
Lymph node (LN) metastasis is considered an important prognostic factor in patients with prostate cancer. The aim of this study was to determine the rate of LN metastasis among an Iranian population who underwent radical prostatectomy (RP) with pelvic LN dissection (PLND). In a retrospective review of medical records, 450 RP cases were included and the data on LN metastasis were extracted from surgical pathology reports.Overall, 4.7% of the patients had LN metastasis. The rate of surgical stage T3 (50% vs. 13.5%; P=0.021) and pathological Gleason score ³7 (82.4% vs. 48.8%; P=0.002) was significantly higher among LN-positive patients. All patients with LN metastasis had a serum prostate specific antigen level >4 ng/ml.The diagnosis of prostate cancer is in an acceptable, but not ideal, stage of the disease; this may be due to screening examinations and tests.

Keywords

Prostate cancer
Prostatectomy
Lymph node dissection
Iranian Journal of Medical Sciences
Volume 39, Issue 2 - Serial Number 2
13
March 2014
Pages 140-143

  • Received 01 March 2014
  • Revised 23 August 2020
  • Accepted 24 December 2018

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