Iranian Journal of Medical Sciences

Document Type: Case Report(s)


1 Department of General Medicine, Sher-e-Kashmir Institute of Medical Sciences, Medical College Hospital, Srinagar, India

2 Department of Ophthalmology, Shri Maharaja Hari Singh Hospital, Srinagar, India

3 Department of Preventive and Social Medicine, Sher-e-Kashmir Institute of Medical Sciences, Soura, Srinagar, India

4 Division of Phaco Surgery, Al-Kabir Medical Center, Srinagar, India


Sheehan’s syndrome or Simmond’s disease is a rare endocrine disorder seen in clinical practice. The clinical spectrum is diverse and a high index of suspicion together with a good clinical acumen and proper diagnostic approach helps in early diagnosis and prompt treatment of this endocrinopathy. Sheehan’s syndrome presenting as a major depressive disorder finds less mention in the literature.The patient discussed here is a 45-year-old female who had been on antidepressants and psychiatry follow up for a long time until she presented to our Out Patient Department (OPD), where she was evaluated in detail and diagnosed as a case of Sheehan’s syndrome. The patient is doing well and is on a regular follow-up with us. Further studies are required to demystify the strength of this association in more detail and to elucidate the possible underlying mechanism.