Iranian Journal of Medical Sciences

Charcot-Leyden Crystals in Hodgkin's Lym-phoma

Document Type : Case Report(s)

Authors

Abstract
Herein, we reported on a middle-aged woman presented with painless cervical lymphadenopathy. Past medical history was not significant. Pathologic examination of incisional biopsy show partial effacement of lymph node architecture with many reactive inflammatory cells admixed with Reed-Sternberg cells, many Charcot-Leyden crystals, and noncaseating granuloma. Immunohistochemical staining was positive for the classic Reed-Sternberg cells for CD15 and CD30 and was negative for CD45 and CD20. All these findings confirmed the diagnosis of Hodgkin's lymphoma. Charcot-Leyden crystals, is considered a morphologic hallmark of eosinophil-related diseases. However, to the best of our knowledge, only one case of Hodgkin's lymphoma has been reported in the world literature who has had Charcot-Leyden crystals.

Keywords


Volume 32, Issue 2 - Serial Number 2
42
June 2007
Pages 124-126

  • Received 25 May 2015
  • Revised 07 March 2021
  • Accepted 24 December 2018