Iranian Journal of Medical Sciences

Efficacy of Permethrin-Impregnated Uniforms in the Prevention of Cutaneous Leishmania-sis in Iranian Soldiers

Document Type : Original Article(s)

Authors

Abstract
Background: One approach for prevention of cutaneous leishmaniasis is creation of a barrier between the insect vector (phlebotomus) and the host.  Many, but not all, researchers claim that permethrin-impregnated uniforms are effective for prevention of cutaneous leishmaniasis.  We determined the efficacy of permethrin-impregnated uniforms for prevention of cutaneous leishmaniasis among Iranian soldiers. Methods: 324 soldiers were randomized into two equal groups.  272 soldiers completed the study.  In Group A, 134 soldiers were issued permethrin impregnated uniforms.  In Group B, 138 soldiers were issued uniforms washed in water.  The soldiers wore uniforms day and night for 3 months, and were observed for an additional 6 months.  All of the soldiers remained during this 3 months in the leishmaniasis-endemic area of Isfahan. Results: 9 (6.5%) of 138 soldiers wearing control uniforms and 6 (4.4%) of 134 soldiers wearing permethrin-impregnated uniforms acquired cutaneous leishmaniasis.  The difference between the two groups was not statistically significant. Conclusion: Permethrin-impregnated uniforms may not be effective in prevention of cutaneous leishmaniasis.

Volume 27, Issue 4 - Serial Number 4
69
December 2002
Pages 172-175

  • Received 30 November 2015
  • Accepted 24 December 2018