Iranian Journal of Medical Sciences

Ostegogenic Sarcoma with Epithelial Differentiation (Carcinosarcoma): Report of Two Cases

Document Type : Case Report(s)

Authors

1 Departments of Pathology, Shiraz University of Medical Sciences, Shiraz

2 Departments of Orthopaedic Surgery, Shiraz University of Medical Sciences, Shiraz

Abstract
Epitheloid osteosarcoma (carcinosarcoma) of the bone is a rare malignant tumor and only a few cases have been reported in the literature. In this study, we report two cases of osseous carcinosarcoma (epitheloid osteosarcoma) with immunohistochemical studies.  The morphological and immunohistochemical data in these two cases support the theory of divergent differentiation of primitive, uncommitted multipotiential stem cell to produce biphenotypic tumors. 

Volume 26, 3-4 - Serial Number 3
73
September 2001
Pages 174-177

  • Received 23 December 2015
  • Accepted 24 December 2018