Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences

Kikuchi-Fujimoto Disease: A Rare Presentation with Localized Iliac Lymphadenitis

Document Type : Case Report(s)

Authors

Shrihari Anil Anikhindi 1
Anil Arora 1
Shashi Dhawan 2
Naresh Bansal 1
Praveen Sharma 1
Vikas Singla 1
Ashish Kumar 1

1 Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi

2 Department of Pathology, Sir Ganga Ram Hospital, New Delhi

Abstract
Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. Though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. It has a female predilection and most commonly seen among young Asian people. Patients usually present with a febrile illness and the presence of lymphadenopathy may provide a clue to diagnosis. The most common site of lymphadenopathy is cervical lymph nodes while intra-abdominal involvement is uncommon. Cases of KFD presenting with intra-abdominal lymphadenopathy have been reported to occur with equal frequency in both sexes. Abdominal tuberculosis, non-Hodgkin’s lymphoma, and systemic lupus erythematosus are close differential diagnoses for this type of presentation. Treatment is mostly supportive as the disease usually resolves spontaneously; steroids are only required in severe cases. We report a 32-year-old male patient of intra-abdominal lymphadenitis that presented as fever of unknown origin (FUO) and diagnosed by excisional biopsy as a case of KFD.

Keywords

Histiocytic necrotising lymphadenitis
Fever of unknown origin
Abdomen
Iranian Journal of Medical Sciences
Volume 42, Issue 1 - Serial Number 1
83
January 2017
Pages 94-97

  • Received 29 March 2015
  • Revised 17 October 2021
  • Accepted 24 December 2018

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