Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences

Eosinophilic Granulomatosis with Polyangiitis Manifested by Cholecystitis and Mononeuritis Multiplex: A Case Report

Document Type : Case Report(s)

Authors

Maryam Mobini 1
Hamed Cheraghmakani 2
Zhila Torabizadeh 3
Omid Emadian 3
Fatemeh Nezhadi Kelarijani 4

1 Diabetes Research Center, Department of Internal Medicine, Mazandaran University of Medical Sciences, Sari, Iran

2 Department of Neurology, Bu Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran

3 Department of Pathology, Mazandaran University of Medical Sciences, Sari, Iran

4 Resident in Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

https://doi.org/10.30476/ijms.2018.40538
Abstract
Eosinophilic granulomatosis with polyangiitis formerly named “Churg-Strauss syndrome (CSS)” is a systemic disease with bronchial asthma, hypereosinophilia, and systemic vasculitis. We report a case of CSS with cholecystitis and mononeuritis multiplex. A 50-year-old woman with a history of sinusitis and bronchial asthma of 8 years’ duration was referred with a complaint of left-hand deformity and difficulty in walking. The laboratory findings included remarkable eosinophilia, an elevated erythrocyte sedimentation rate, and a marked eosinophilic infiltration in the gallbladder biopsy. Based on the clinical features and histopathological findings, she was diagnosed with CSS and subsequently treated with prednisolone and cyclophosphamide.

Keywords

Churg-Strauss syndrome
Cholecystitis
Mononeuropathies

  • Received 30 December 2016
  • Revised 15 March 2020
  • Accepted 24 December 2018

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