Iranian Journal of Medical Sciences

Document Type : Case Series


1 Department of Radiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

3 Department of Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran



Bronchopleural fistula (BPF), a sinus tract between the bronchial system and the pleural space, is associated with COVID-19 and can lead to pneumothorax, which increases the mortality rate. Due to the analytical status of COVID-19 patients, sealing the BPF necessitates the least minimal invasive treatment. Herein, we demonstrated a technique of sealing post-COVID-19 BPF with direct injection of cyanoacrylate glue under the guidance of a computed tomography scan. Following glue injection, the BPF was completely sealed in all four patients. In conclusion, in COVID-19 patients with small and distal BPF, percutaneous glue injection is recommended for BPF closure.


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