Iranian Journal of Medical Sciences

Document Type : Original Article(s)

Authors

1 Bone and Joint Diseases Research Center, Department of Orthopedics, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Orthopedics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

3 Dena Hospital, Shiraz, Iran

10.30476/ijms.2024.100363.3265

Abstract

Background: Knee arthroplasty procedures improve pain, function, stability, and appearance of the limb. Total knee arthroplasty (TKA) in severe, long-standing osteoarthritis (OA) with large medial tibial defects could be a challenge. This paper looks at TKA outcomes when large tibial defects are managed without metal wedges or stems.
Methods: TKA cases done for OA with tibial defects of 15-25 mm, without any metal wedge or stem from 2004 to 2017 by a single surgeon in Shiraz, Iran, were clinically and radiographically evaluated. The preoperative questionnaires of SF36, WOMAC, KSS, and radiographs were compared with the follow-up assessments of the same parameters. Data were analyzed by R programming language using student t test, ANOVA, and Kruskal-Wallis. P<0.05 was considered significant. 
Results: 91 knees in 72 patients at 65.99±8.66 years of age and 8.28±2.58 years follow-up were studied. The tibial defects were managed with extra tibial cuts and adjustment of tibial component position in all, and the addition of structural autograft in 14 knees. 89 (98%) knees survived with a knee society score (KSS) of 79.4±17.6 and were significantly functioning well (P<0.001). Two knees required revision surgery. Significant improvement in outcome measurements was seen in all cases (P<0.001). No radiographic loosening, alignment change, or clinical instability was detected. The tibial plateau reconstruction without bone grafting and the ones that had autologous bone grafting had similar functional results and radiographic outcomes.
Conclusion: TKA with tibial defects of 15-25 mm treated with a semi-constrained posterior-cruciate ligament (PCL) sacrificing condylar prosthesis without any metal wedges or stem extensions with or without additional autogenous bone graft obtained very good functional and radiographic outcome and 97% survival in 6-17 years follow-up.

Keywords

  1. Jauregui JJ, Cherian JJ, Pierce TP, Beaver WB, Issa K, Mont MA. Long-Term Survivorship and Clinical Outcomes Following Total Knee Arthroplasty. J Arthroplasty. 2015;30:2164-6. doi: 10.1016/j.arth.2015.05.052. PubMed PMID: 26100473.
  2. Koskinen E, Paavolainen P, Ylinen P, Eskelinen A, Harilainen A, Sandelin J, et al. Mid-term results for three contemporary total knee replacement designs - a comparative study of 104 patients with primary osteoarthritis. Scand J Surg. 2010;99:250-5. doi: 10.1177/145749691009900414. PubMed PMID: 21159598.
  3. Shahcheraghi G, Javid M, Mahmoodian B. Functional outcome study in total knee arthroplasty. Iran J Med Sci. 2015;29:151-6.
  4. Kharbanda Y, Sharma M. Autograft reconstructions for bone defects in primary total knee replacement in severe varus knees. Indian J Orthop. 2014;48:313-8. doi: 10.4103/0019-5413.132525. PubMed PMID: 24932040; PubMed Central PMCID: PMCPMC4052033.
  5. Abdel MP, Bonadurer GF, 3rd, Jennings MT, Hanssen AD. Increased Aseptic Tibial Failures in Patients With a BMI >/=35 and Well-Aligned Total Knee Arthroplasties. J Arthroplasty. 2015;30:2181-4. doi: 10.1016/j.arth.2015.06.057. PubMed PMID: 26220103.
  6. Hosaka K, Saito S, Oyama T, Fujimaki H, Cho E, Ishigaki K, et al. Union, Knee Alignment, and Clinical Outcomes of Patients Treated With Autologous Bone Grafting for Medial Tibial Defects in Primary Total Knee Arthroplasty. Orthopedics. 2017;40:e604-e8. doi: 10.3928/01477447-20170418-01. PubMed PMID: 28437545.
  7. Mounasamy V, Ma SY, Schoderbek RJ, Mihalko WM, Saleh KJ, Brown TE. Primary total knee arthroplasty with condylar allograft and MCL reconstruction for a comminuted medial condyle fracture in an arthritic knee--a case report. Knee. 2006;13:400-3. doi: 10.1016/j.knee.2006.06.006. PubMed PMID: 16875826.
  8. Panegrossi G, Ceretti M, Papalia M, Casella F, Favetti F, Falez F. Bone loss management in total knee revision surgery. Int Orthop. 2014;38:419-27. doi: 10.1007/s00264-013-2262-1. PubMed PMID: 24407821; PubMed Central PMCID: PMCPMC3923937.
  9. Morgan H, Battista V, Leopold SS. Constraint in primary total knee arthroplasty. J Am Acad Orthop Surg. 2005;13:515-24. doi: 10.5435/00124635-200512000-00004. PubMed PMID: 16330513.
  10. Pour AE, Parvizi J, Slenker N, Purtill JJ, Sharkey PF. Rotating hinged total knee replacement: use with caution. J Bone Joint Surg Am. 2007;89:1735-41. doi: 10.2106/JBJS.F.00893. PubMed PMID: 17671012.
  11. Parratte S, Ollivier M, Lunebourg A, Verdier N, Argenson JN. Do Stemmed Tibial Components in Total Knee Arthroplasty Improve Outcomes in Patients With Obesity? Clin Orthop Relat Res. 2017;475:137-45. doi: 10.1007/s11999-016-4791-6. PubMed PMID: 26992719; PubMed Central PMCID: PMCPMC5174024.
  12. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15:1833-40. PubMed PMID: 3068365.
  13. Ebrahimzadeh MH, Makhmalbaf H, Birjandinejad A, Keshtan FG, Hoseini HA, Mazloumi SM. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in Persian Speaking Patients with Knee Osteoarthritis. Arch Bone Jt Surg. 2014;2:57-62. PubMed PMID: 25207315; PubMed Central PMCID: PMCPMC4151432.
  14. Ware JE, Jr., Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473-83. PubMed PMID: 1593914.
  15. Motamed N, Ayatollahi AR, Zare N, Sadeghi-Hassanabadi A. Validity and reliability of the Persian translation of the SF-36 version 2 questionnaire. East Mediterr Health J. 2005;11:349-57. PubMed PMID: 16602453.
  16. Scuderi GR, Bourne RB, Noble PC, Benjamin JB, Lonner JH, Scott WN. The new Knee Society Knee Scoring System. Clin Orthop Relat Res. 2012;470:3-19. doi: 10.1007/s11999-011-2135-0. PubMed PMID: 22045067; PubMed Central PMCID: PMCPMC3237971.
  17. Mirahmadi A, Hosseini-Monfared P, Amiri S, Taheri F, Farokhi M, Minaei Noshahr R, et al. Crosscultural adaptation and validation of the Persian version of the new Knee Society Knee Scoring System (KSS). J Orthop Surg Res. 2023;18:858. doi: 10.1186/s13018-023-04347-7. PubMed PMID: 37953297; PubMed Central PMCID: PMCPMC10641991.
  18. Sugita T, Aizawa T, Sasaki A, Miyatake N, Fujisawa H, Kamimura M. Autologous morselised bone grafting for medial tibial defects in total knee arthroplasty. J Orthop Surg (Hong Kong). 2015;23:185-9. doi: 10.1177/230949901502300214. PubMed PMID: 26321547.
  19. Ahmed I, Logan M, Alipour F, Dashti H, Hadden WA. Autogenous bone grafting of uncontained bony defects of tibia during total knee arthroplasty a 10-year follow up. J Arthroplasty. 2008;23:744-50. doi: 10.1016/j.arth.2007.08.021. PubMed PMID: 18534492.
  20. Cuckler JM. Bone loss in total knee arthroplasty: graft augment and options. J Arthroplasty. 2004;19:56-8. doi: 10.1016/j.arth.2004.03.002. PubMed PMID: 15190551.
  21. Dorr LD, Ranawat CS, Sculco TA, McKaskill B, Orisek BS. Bone graft for tibial defects in total knee arthroplasty. 1986. Clin Orthop Relat Res. 2006;446:4-9. doi: 10.1097/01.blo.0000214430.19033.b3. PubMed PMID: 16672862.
  22. Qiu YY, Yan CH, Chiu KY, Ng FY. Review article: bone defect classifications in revision total knee arthroplasty. J Orthop Surg (Hong Kong). 2011;19:238-43. doi: 10.1177/230949901101900223. PubMed PMID: 21857054.
  23. Bole M, Teeter M, Lanting BA, Howard JL. Correlation of tibial bone defect shape with patient demographics following total knee revision. J Orthop. 2018;15:490-4. doi: 10.1016/j.jor.2018.03.025. PubMed PMID: 29643692; PubMed Central PMCID: PMCPMC5889696.
  24. Yoon JR, Seo IW, Shin YS. Use of autogenous onlay bone graft for uncontained tibial bone defects in primary total knee arthroplasty. BMC Musculoskelet Disord. 2017;18:502. doi: 10.1186/s12891-017-1826-4. PubMed PMID: 29187180; PubMed Central PMCID: PMCPMC5706337.
  25. Brand MG, Daley RJ, Ewald FC, Scott RD. Tibial tray augmentation with modular metal wedges for tibial bone stock deficiency. Clin Orthop Relat Res. 1989:71-9. doi: 10.1097/00003086-198911000-00013. PubMed PMID: 2805499.
  26. Ramkumar PN, Harris JD, Noble PC. Patient-reported outcome measures after total knee arthroplasty: a systematic review. Bone Joint Res. 2015;4:120-7. doi: 10.1302/2046-3758.47.2000380. PubMed PMID: 26220999; PubMed Central PMCID: PMCPMC4602194.
  27. Verra WC, van den Boom LG, Jacobs W, Clement DJ, Wymenga AA, Nelissen RG. Retention versus sacrifice of the posterior cruciate ligament in total knee arthroplasty for treating osteoarthritis. Cochrane Database Syst Rev. 2013;2013:CD004803. doi: 10.1002/14651858.CD004803.pub3. PubMed PMID: 24114343; PubMed Central PMCID: PMCPMC6599815.
  28. Argenson JN, Boisgard S, Parratte S, Descamps S, Bercovy M, Bonnevialle P, et al. Survival analysis of total knee arthroplasty at a minimum 10 years’ follow-up: a multicenter French nationwide study including 846 cases. Orthop Traumatol Surg Res. 2013;99:385-90. doi: 10.1016/j.otsr.2013.03.014. PubMed PMID: 23644031.
  29. Pagnano MW, Trousdale RT, Rand JA. Tibial wedge augmentation for bone deficiency in total knee arthroplasty. A followup study. Clin Orthop Relat Res. 1995:151-5. doi: 10.1097/00003086-199512000-00023. PubMed PMID: 7497661.
  30. Rawlinson JJ, Closkey RF, Jr., Davis N, Wright TM, Windsor R. Stemmed implants improve stability in augmented constrained condylar knees. Clin Orthop Relat Res. 2008;466:2639-43. doi: 10.1007/s11999-008-0424-z. PubMed PMID: 18709431; PubMed Central PMCID: PMCPMC2565014.
  31. Mohammad HR, Judge A, Murray DW. The Effect of Body Mass Index on the Relative Revision Rates of Cemented and Cementless Unicompartmental Knee Replacements: An Analysis of Over 10,000 Knee Replacements from National Databases. J Bone Joint Surg Am. 2023;105:527-36. doi: 10.2106/JBJS.22.01042. PubMed PMID: 36881643.