Document Type : Letter(s) to the Editor
Author
Iranian Centre for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
10.30476/ijms.2026.110774.4655
Abstract
I read with interest the recent case report by Jafari and colleagues describing the use of exosomes derived from human umbilical cord mesenchymal stromal/stem cells (hUCMSCs) in a mandibular premolar diagnosed with irreversible pulpitis and treated with pulpectomy.
Highlights
Saeed Asgary (Google Scholar)
Keywords
- Jafari N, Seyed Habashi M, Afshar A, Ghasemi M, Kurmanalina MA, Mussin NM, et al. The Effect of Exosomes Derived from Human Umbilical Cord Mesenchymal Stromal/Stem Cells on the Regeneration of Human Pulpectomized Tooth: A Case Report. Iran J Med Sci. 2025;50:54-8. doi: 10.30476/ijms.2024.103117.3638. PubMed PMID: 39957811; PubMed Central PMCID: PMC11829066.
- Shi J, Teo KYW, Zhang S, Lai RC, Rosa V, Tong HJ, et al. Mesenchymal stromal cell exosomes enhance dental pulp cell functions and promote pulp-dentin regeneration. Biomater Biosyst. 2023;11:100078. doi: 10.1016/j.bbiosy.2023.100078. PubMed PMID: 37283805; PubMed Central PMCID: PMC10239699.
- Asgary S, Nosrat A. Vital Pulp Therapy: Evidence-Based Techniques and Outcomes. Iran Endod J. 2025;20:e2. doi: 10.22037/iej.v20i1.47141. PubMed PMID: 39935864; PubMed Central PMCID: PMC11808331.
- Santos JM, Pereira JF, Marques A, Sequeira DB, Friedman S. Vital Pulp Therapy in Permanent Mature Posterior Teeth with Symptomatic Irreversible Pulpitis: A Systematic Review of Treatment Outcomes. Medicina (Kaunas). 2021;57. doi: 10.3390/medicina57060573. PubMed PMID: 34205149; PubMed Central PMCID: PMC8228104.
- Asgary S, Roghanizadeh L, Eghbal MJ, Akbarzadeh Baghban A, Aminoshariae A, Nosrat A. Outcomes and predictive factors of vital pulp therapy in a large-scale retrospective cohort study over 10 years. Sci Rep. 2024;14:2063. doi: 10.1038/s41598-024-52654-8. PubMed PMID: 38267594; PubMed Central PMCID: PMC10808198.
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